Stephen D. Silberstein, MD; Joseph Hulihan, MD; M. Rezaul Karim, PhD; Shu-Chen Wu, PhD; Donna Jordan, MD; Debra Karvois, MS; and Marc Kamin, MD (2006): Efficacy and Tolerability of Topiramate 200 mg/d in the Prevention of Migraine With/Without Aura in Adults: A Randomized, Placebo-Controlled, Double-Blind, 12-Week Pilot Study. Clinical Therapeutics, 28(7): 1002-1011.  

Akpunonu B, Michaelis J, Uy C N, Tennenberg A M, Wiesinger B A, Karim R, Marshall S, Kahn J B (2004): Multicenter, Postmarketing Assessment of Levofloxacin in the Treatment of Adults with Community-Acquired Pneumonia. Clinical Infectious Diseases, 38 (Suppl 1): S5-S15.  

Dawson W. Hedges, M.D.; Frederick W. Reimherr, M.D.; Scott P. Hoopes, M.D.; Norman R. Rosenthal, M.D.; Marc Kamin, M.D.; Rezaul Karim, Ph.D.; and Julie A. Capece, B.A. (2003): Treatment of Bulimia Nervosa With Topiramate in a Randomized, Double-Blind, Placebo-Controlled Trial, Part 2: Improvement in Psychiatric Measures. Journal of Clinical Psychiatry, 64 (12): 1449-1454.  

Scott P. Hoopes, M.D.; Frederick W. Reimherr, M.D.; Dawson W. Hedges, M.D.; Norman R. Rosenthal, M.D.; Marc Kamin, M.D.; Rezaul Karim, Ph.D.; Julie A. Capece, B.A.; and Debra Karvois, M.S. (2003): Treatment of Bulimia Nervosa With Topiramate in a Randomized, Double-Blind, Placebo-Controlled Trial, Part 1: Improvement in Binge and Purge Measures. Journal of Clinical Psychiatry, 64 (11): 1335-1341.  

Robert M. Bennett, MD, Marc Kamin, MD, Rezaul Karim, PhD, Norman Rosenthal, MD (2003): Tramadol and acetaminophen combination tablets in the treatment of fibromyalgia pain: a double-blind, randomized, placebo-controlled study. American Journal of Medicine, 114 (7): 537-545.  

Gary E. Ruoff, MD, Norman Rosenthal, MD, Donna Jordan, BSN, Rezaul Karim, PhD, and Marc Kamin, MD, on behalf of the Protocol CAPSS-112 Study Group (2003): Tramadol/Acetaminophen Combination Tablets for the Treatment of Chronic Lower Back Pain: A Multicenter, Randomized, Double-Blind, Placebo-Controlled Outpatient Study. Clinical Therapeutics, 25(4): 1123-1141.  

K.J. Meador, MD; D.W. Loring, PhD; J.F. Hulihan, MD; M. Kamin, MD; and R. Karim, PhD, for the CAPSS-027 Study Group (2003): Differential cognitive and behavioral effects of topiramate and valproate. Neurology, 60: 1483-1488.  

Susan L. McElroy, M.D., Lesley M. Arnold, M.D., Nathan A. Shapira, M.D., Ph.D., Paul E. Keck, Jr., M.D., Norman R. Rosenthal, M.D., M. Rezaul Karim, Ph.D., Marc Kamin, M.D., James I. Hudson, M.D., Sc.D. (2003): Topiramate in the Treatment of Binge Eating Disorder Associated With Obesity: A Randomized, Placebo-Controlled Trial. American Journal of Psychiatry, 160: 255-261.  

Fricke J.R.; Karim R.; Jordan D.; and Rosenthal N. (2002): A Double-Blind, Single-Dose Comparison of the Analgesic Efficacy of Tramadol/Acetaminophen Combination Tablets, Hydrocodone/Acetaminophen Combination Tablets, and Placebo After Oral Surgery. Clinical Therapeutics, 24(6): 953-968.  

Barbara H. Perry, Ph.D., Allan R. Sampson, Ph.D., Barry H. Schwab, Ph.D., M. Rezaul Karim, Ph.D., Janice M. Smiell, M.D. (2002): A meta-analytic approach to an integrated summary of efficacy: a case study of becaplermin gel. Controlled Clinical Trials, 23(2002) 389-409.  

Julia Wang, Rezaul Karim, and Robert Medve (2001): The Role of Bootstrap in Study Design. ASA Proceedings of the Biopharmaceutical Section, 0: 100-104.  

d’Hemecourt, P.A., Smiell, J.M., and Karim, M.R. (1998): Sodium Carboxymethylcellulose Aqueous-Based Gel vs. Becaplermin Gel in Patients with Nonhealing Lower Extremity Diabetic Ulcers. Wounds, 10(3): 69-75.  

E. Faught, MD; B.J. Wilder, MD; R.E. Ramsay, MD; R.A. Reife, MD; L.D. Kramer, MD; G.W. Pledger, PhD; R.M. Karim, PhD; and the Toparamate Study Group (1996): Topiramate Placebo-Controlled Dose-Ranging Trial in Refractory Partial Epilepsy Using 200-, 400-, and 600-mg Daily Dosages. Neurology, 46(6), 1684-90.  

Sharief, M., Viteri, C., Ben-Menachem, E., Weber, M., Reife, R., Pledger, G., and Karim, R. (1996): Double-Blind, Placebo-Controlled Study of Topiramate in Patients With Refractory Partial Epilepsy. Epilepsy Research, 25(3), 217-24.  

Tassinari, C.A., Michelucci, R., Chauvel, P., Chodkiewicz, J., Shorvon, S., Henriksen, O., Dam, M., Reife, R., Pledger, G., and Karim R. (1996): Double-Blind, Placebo-Controlled Trial of Topiramate (600 mg Daily) in the Treatment of Refractory Partial Epilepsy. Epilepsia, 37(8), 763-8.  

Privitera, M., Fincham, R., Penry, J., Reife, R., Pledger, G., and Karim, R. (1996): Topiramate Placebo-Controlled Dose-Ranging Trial in Refractory Partial Epilepsy Using 600-, 800-, and 1,000-mg Daily Dosages. Neurology, 46(6), 1678-83.  

Ben-Menachem, E., Henriksen, O., Dam, M., Mikkelsen, M., Schmidt, D., Reid, S., Reife, R., Kramer, L., Pledger, G., and Karim, R. (1996): Double-Blind, Placebo-Controlled Trial of Topiramate as Add-On Therapy in Patients with Refractory Partial Seizures. Epilepsia, 37(6), 539-43.  

M. Rezaul Karim, and Scott L. Zeger (1992): Generalized Linear Models With Random Effects; Salamander Mating Revisited. Biometrics, 48: 631-644.  

Scott L. Zeger, and M. Rezaul Karim (1991): Generalized Linear Models With Random Effects; A Gibbs Sampling Approach. Journal of the American Sattistical Association, 86: 79-86.  

Bhuiya, A, Wojtyniak, B, and Karim, R. (1989): Malnutrition and child mortality: Are socioeconomic factors important? Journal of Biosocial Science, 21:357-364.  

Berdeaux D, Tennenberg A, Wiesinger B, Willmann M, Khashab M, Karim R, Kahn J (2002): A Multicenter, Randomized Study to Compare the Safety and Efficacy of Oral Levofloxacin vs. Parenteral Ceftriaxone and Amikacin With the Potential of Conversion to Oral Ciprofloxacin and Amoxicillin/Clavulanate in the Treatment of Talcott Group IV Subjects with Febrile Neutropenia. Poster pesented at the 10th International Congress on Infectious Diseases (ICID); Singapore, March 11-14, 2002.

Kahn J B, Wiesinger B A, Scott-Marshall J S, Olson W H, Karim R (2000): Levofloxacin in the Treatment of Community-Acquired Pneumonia Due to Penicillin-Resistant and -Susceptible Pneumococci and Other Pathogens. Abstract pesented at the 38th Annual Meeting of The Infectious Diseases Society of America (IDSA 2000); New Orleans, LA, September 7-10, 2000. [Abstract 172]

Kahn J B, Wiesinger B A, Scott-Marshall J S, Olson W H, Karim R (2000): Open-Label, Multicenter Assessment of Levofloxacin in the Treatment of Community-Acquired Pneumonia Caused by Penicillin-Resistant Pneumococci and other Pathogens. Poster pesented at the 38th Annual Meeting of The Infectious Diseases Society of America (IDSA 2000); New Orleans, LA, September 7-10, 2000. [Poster 120?]

Hoopes S, Reimherr F, Kamin M, Karvois D, Rosenthal N, Karim R, Capece J (2003): Topiramate in the Treatment of Bulimia Nervosa. Poster presented at Symposium "From Receptor to Reintegration: A Decade of Success Success and Innovation"; Monte Carlo, Monaco, March 7-8, 2003.

Reimherr F, Hoopes S, Karvois D, Karim R, Kamin M, Rosenthal N (2003): Topiramate in the Treatment of Bulimia Nervosa: Additional Efficacy. Poster presented at Symposium "From Receptor to Reintegration: A Decade of Success Success and Innovation"; Monte Carlo, Monaco, March 7-8, 2003.

Silberstein S, Karim R, Kamin M, Jordan D, Hulihan J (2002): Topiramate prophylaxis in patients suffering from migraine with aura: results from a randomized, double-blind, placebo-controlled trial. 6th Congress of the European Federation of Neurological Societies, Vienna, Austria, October 26-29, 2002. [Eur J Neurol; 9 (Suppl 2): 44 (Abs SC 317)]

Freitag F G, Silberstein S D, Karim R, Jordan D, Hulihan J (2002): Topiramate prophylaxis in patients suffering from migraine with aura: results from a randomized, double-blind, placebo-controlled trial. Platform presentation at 14th Migraine Trust International Symposium, London, UK, September 26, 2002. [Cephalalgia; 22 (7): 579 (Abs 84)]

Silberstein S D, Karim R, Jordan D, Hulihan J (2002): Treatment effect for topiramate in migraine prophylaxis: utility of repeated measures and weighted regression analyses. Abstracts and Posters from the 14th Migraine Trust International Symposium, London, UK, September 23-26, 2002. [Cephalalgia; 22 (7): 610 (Abs PB.39)]

Hoopes S P, Reimherr F W, Kamin M, Karvois D, Rosenthal N E, Karim R (2002): Topiramate Treatment of Bulimia Nervosa Abstracts and Posters presented at the 155th Annual Meeting of the American Psychiatric Association (APA), Philadelphia, PA, May 18-23, 2002. [Abstract 7]

Reimherr F W, Hoopes S P, Karvois D, Karim R, Kamin M, Rosenthal N E (2002): Topiramate in the Treatment of Bulimia Nervosa: Additional Efficacy Abstracts and Posters presented at the 155th Annual Meeting of the American Psychiatric Association (APA), Philadelphia, PA, May 18-23, 2002. [Abstract NR474, Poster 732]

Silberstein S, Hulihan J, Kamin M, Karim R (2002): Topiramate in Migraine Prevention: A Randomized, Double-Blind Placebo-Controlled Trial Abstracts and Posters Presented at the 44th Annual Scientific Meeting of the American Headache Society (AHS), Seattle, Washington, June 21-23, 2002. [Headache; 42 (5): 399 (Abs OR28)]

Meador K J, Hulihan J, Kamin M, Karim R (2001): Topiramate (TPM) and Valproate (VPA) Added to Carbamazepine (CBZ): Effect on Objective Measures of Cognitive Function in Adults with Epilepsy Abstracts and Posters of the American Epilepsy Society / American Clinical Neurophysiology Society Annual Meeting; Philadelphia, Pennsylvania, November 30 - December 5, 2001. [Epilepsia; 42 (Suppl 7): 251-252 (Abs 3.103)]

Naritoku D K, Hulihan J, Kamin M, Karim R, Olsen W H, Karvois D (2001): Reduction of AED Co-Therapy Improves Tolerability of Add-On Therapy with Topiramate: A Novel Randomized Study Abstracts of the American Epilepsy Society / American Clinical Neurophysiology Society Annual Meeting; Philadelphia, Pennsylvania, November 30 - December 5, 2001. [Epilepsia; 42 (Suppl 7): 258-259 (Abs 3.126)]

Meador K J, Kamin M, Hulihan J, Karim R (2001): Cognitive function in adults with epilepsy; effect of Topiramate and Valproate added to Carbamazepine Abstracts of the 24th International Epilepsy Congress (IEC); Buenos Aires, Argentina, May 13-17, 2001. [Abs E-0330]

Loring D W, Kamin M, Karim R (2001): Topiramate and Valproate Added to Carbamazepine: Effect on Cognitive Function in Adults with Epilepsy Abstracts and Posters of the 53rd Annual Meeting of the American Academy of Neurology, Philadelphia, PA, May 5-11, 2001. [Neurology; 56 (Suppl 3): A334]

Loring D W, Kamin M, Karim R (0000): TOPIRAMATE (TPM) OR VALPROATE (VPA) ADDED TO CARBAMAZEPINE (CBZ) IN ADULTS WITH EPILEPSY: EFFECTS ON SUBJECTIVE AND OBJECTIVE MEASURES OF COGNITIVE FUNCTION Abstract Presented at the ECE in Florence, Italy. [JCTX-0168]

Reife R, Pledger G, Lim P, Karim R (1997): Patients Achieving >75% and 100% Seizure Reductions in Double-Blind Trials of Topiramate Poster Presentations from the 22nd International Epilepsy Congress; Dublin, Ireland, Jun 29-Jul 4, 1997. [Epilepsia; 38 (Suppl 3): 59]

Reife R, Pledger G, Lim P, Karim R (1996): Topiramate: Pooled Analysis of Six Placebo-Controlled Trials. Abstracts from the Second European Congress of Epileptology, The Hague, The Netherlands. September 1-5, 1996. [Epilepsia; 37 (Suppl 4): 74 (Abs)]

Pledger G, Reife R, Lim P, Karim R (1996): OVERVIEW OF TOPIRAMATE EFFICACY FROM ADJUNCTIVE THERAPY TRIALS Boll Lega Ital Epilessia; 0 (95-96): 247-250 1996.

Pledger G, Reife R A, Lim P, Karim R (1995): Overview of topiramate efficacy from adjunctive therapy trials Abstracts and Posters from the 21st International Epilepsy Congress, Sydney, Australia, September 3 - 8, 1995. [Epilepsia; 36 (3): S150, Poster 193]

Viteri C, Martinez-Lage J, Ben-Menachem E, Shorvon S, Weber M, Karim R, Reife R, Pledger G (1995): Double-Blind, Placebo-Controlled Trial of 400 mg/day Topiramate as Add-On Therapy in Patients with Refractory Partial Epilepsy Abstracts and Posters from the 21st International Epilepsy Congress, Sydney, Australia, September 3 - 8, 1995. [Epilepsia; 36 (Suppl3): S149, Poster 189]

Borenstein D.G., Kamin M., Karim M., Rosenthal N.R., Nguyen R.P. (0000): Combination tramadol and acetaminophen (Ultracet) for the treatment of chronic lower back pain: Improvement in quality of life measures Annals of the Rheumatic Diseases ( Ann. Rheum. Dis. ) 62/SUPPL. 1 (xxx)

Peloso P, Rosenthal N, Jordan D, Karim R, Hewitt D J (2003): Tramadol/Acetaminophen Combination Tablets (ULTRACET) for Chronic Lower Back Pain: Pooled Analysis Poster and Abtracts of the 22nd Annual Scientific Meeting of the American Pain Society; Chicago, IL, March 20-23, 2003. [J Pain; 4 (2, Suppl 1): 26 (Abs 699), Poster #699]

Rosenthal N, Peloso P, Jordan D, Karim R (2002): A Pooled Analysis of the Efficacy and Safety of Tramadol/Acetaminophen Combination Tablets (ULTRACET) in Chronic Lower Back Pain: Quality of Life Measures Posters and Abstracts presented at the 2002 Annual Scientific Meeting of the American College of Rheumatology (ACR) and Association of Rheumatology Health Professionals (ARHP); New Orleans, LA, October 25-29, 2002. [Poster 186]

Fricke J R, Rosenthal N, Karim R (2002): TRAMADOL/ACETAMINOPHEN TABLETS (ULTRACET) VERSUS HYDROCODONE BITARTRATE/ACETAMINOPHEN FOR DENTAL PAIN Posters and abstracts of the 80th General Sesion of the International Association for Dental Research; the 31st Annual Meeting of the American Association for Dental Research, the 26th Annual Meeting of the California Association for Dental Research, San Diego, CA, March 6-9, 2002. [J Dent Res; 81 (SPEC ISSUE): A189]

Bennett R M, Kamin M, Rosenthal N, Karim R, Capss-113 Study Group (2001): EFFICACY AND SAFETY OF A TRAMADOL/ACETAMINOPHEN COMBINATION (ULTRACET(R)) IN THE MANAGEMENT OF FIBROMYALGIA RELATED PAIN: A MULTICENTER, OUTPATIENT, RANDOMIZED, DOUBLE-BLIND, PLACEBO-CONTROLLED STUDY Abstract and Poster of American College of Rheumatology 65th Annual Scientific Meeting, Association of Rheumatology Health Professionals 36th Annual Scientific Meeting, San Francisco, CA, November 10-15, 2001. [Arthritis Rheum; 44 (9, Suppl): S67 (Ab 90)]

Borenstein D G, Kamin M, Rosenthal N, Karim R, Capss-112 Study Group (2001): COMBINATION TRAMADOL AND ACETAMINOPHEN (ULTRACET(R)) FOR THE TREATMENT OF CHRONIC LOWER BACK PAIN: A MULTICENTER, OUTPATIENT, RANDOMIZED, DOUBLE-BLIND, PLACEBO-CONTROLLED STUDY Abstract and Poster of American College of Rheumatology 65th Annual Scientific Meeting, Association of Rheumatology Health Professionals 36th Annual Scientific Meeting, San Francisco, CA, November 10-15, 2001. [Arthritis Rheum; 44 (9, Suppl): S67 (Ab 89)]

Medve R A, Wang J, Karim R (2001): Tramadol and Acetaminophen Tablets for Dental Pain [Anesth Prog; 48 (3): 79-81]